PHA Series Pharmaceutical-Grade Silicone Tubing

Characteristicse

• vailable in PHA50, PHA60, PHA65, and PHA80 grades
• Supports general fluid transfer, peristaltic pumping, and pressure-rated applications
• Sizes range from 1/32″ (0.8 mm) to 1″ (25.4 mm)
• Supports both gamma irradiation and autoclave sterilization
• Offered in standard 7.5 m and 15 m coil lengths
• Shelf life of up to 3 years
• Backed by comprehensive biocompatibility and validation documentation

Application

Upstream Processing

• Transfer of media, feeds, and process buffers
• Transfer of cell culture and harvest fluids
• Peristaltic pump applications for intermittent and continuous feeding

Downstream Processing

• Preparation and transfer of chromatography buffers acid and caustic reagents
• Fluid transfer in depth filtration, ultrafiltration, and purification processes
• General fluid management across downstream operations

Fill-Finish and Advanced Therapies

• Fluid pathways for in-process control bulk drug substance preparation and formulation
• Assembly and integration of single-use systems
• Fluid transfer for aseptic manufacturing applications

Advantage

• Broad Product Portfolio:Multiple tubing grades support a wide range of process requirements, from general transfer to pumping and pressure applications.
• High-Purity Silicone Materia:Low protein binding and low extractables help maximize product recovery and reduce process loss.
• Regulatory Support:Comprehensive validation documentation helps accelerate qualification, process change, and regulatory filing activities.
• Proven Across Process Scales:Suitable for use in process development, pilot-scale manufacturing, and commercial production.
• Reliable Supply:Manufactured under controlled production processes to provide stable product quality and dependable supply continuity.